Download e-book for iPad: Amino Acids - A Medical Dictionary, Bibliography, and by Icon Health Publications, Health Publica Icon Health

By Icon Health Publications, Health Publica Icon Health Publications

ISBN-10: 0597836949

ISBN-13: 9780597836947

It is a 3-in-1 reference publication. It supplies a whole clinical dictionary overlaying hundreds of thousands of phrases and expressions in relation to amino acids. It additionally supplies large lists of bibliographic citations. ultimately, it offers details to clients on the best way to replace their wisdom utilizing quite a few net assets. The publication is designed for physicians, scientific scholars getting ready for Board examinations, scientific researchers, and sufferers who are looking to get to grips with learn devoted to amino acids. in case your time is efficacious, this booklet is for you. First, you won't waste time looking out the net whereas lacking loads of proper info. moment, the ebook additionally saves you time indexing and defining entries. eventually, you won't waste time and cash printing hundreds of thousands of websites.

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Additional info for Amino Acids - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References

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Since they catalyze the inactivation of several known carcinogens, these enzymes can provide a defense against carcinogenesis. On the other hand, the elevation of GST levels in solid tumors appears to be a major factor in the development of resistance to treatment with cytotoxic agents. The GSTs are grouped into at least six different gene families based on sequence similarity and substrate specificity; and these isozymes differ in their ability to confer resistance to particular anti-cancer drugs.

The specific aims of our research are the following: 1 & 2) To use self-complementary facially amphiphilic derivatives of glycoluril to perform hydrophobic self-assembly in water. To determine the molecular level structural and thermodynamic details of these complexes and identify selective pairwise interactions that may be used to form well-defined thermodynamically stable (1 microM) aggregates in a predictable manner. 3) We will determine the energetic costs associated with changes in conformational entropy that occur during the "folding" of dimeric facial amphiphiles in water 4 &5) We use complex non-natural facially amphiphilic oligomers to target the recognition of amino acids, peptides and protein surfaces in water.

Involvement of Cr(III) in the DNA adduction in vivo will be studied in mammalian cells following their exposure to Cr(VI) or particulate Cr(III) compounds. In addition, the role of nucleotide excision repair in the removal of different Cr(III) adducts will also be analyzed. The results of the proposed work will help understand molecular mechanisms of Cr(VI) carcinogenicity by testing a Cr(III)-dependent pathway of DNA damage and mutagenicity of major adducts. Clarification of the genotoxic activity of intracellular Cr(III) may also have important public health implications considering the fact that human exposure frequently occurs to mixtures of Cr(VI) and Cr(III) forms while current risk assessment is based predominantly on the Cr(VI) levels.

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Amino Acids - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by Icon Health Publications, Health Publica Icon Health Publications

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